QuantideX® BCR-ABL
Sensitive | Reliable | Simple 
The QuantideX® BCR-ABL qPCR portfolio offers easy-to-implement testing solutions for the sensitive and reliable quantitation of Major (e13a2, e14a2) transcripts for chronic myeloid leukemia (CML) monitoring and minor (e1a2) BCR-ABL1 fusion transcript for clinical research.
For Clinical Applications
The QuantideX® qPCR BCR-ABL IS Kit is an FDA-cleared, clinically-proven method for CML monitoring with best-in-class sensitivity (MR4.7). With its simple and streamlined workflow, any molecular lab can deliver accurate and clinically-meaningful results that physicians can trust to guide patient therapy.
For Research Applications
The QuantideX® qPCR BCR-ABL minor Kit* extends the portfolio to provide labs and clinical researchers with a unique, robust and reliable tool to examine the biology of disease and insights for this very rare but distinct leukemic variant.
Reduced Complexity
- Direct reporting on the IS†: Multi-point standard curve reduces variability and removes need for costly, complex sample exchange programs
- End-to-end workflow: Automated results reporting using QuantideX® Reporter software
Optimized Workflow
- Reduced hands-on time: Multiplexed design amplifies and detects both fusion and control gene in the same reaction
- Simplified inventory & quality management: All necessary RT and qPCR reagents and controls supplied in a single kit
- Common assay workflows across Major & minor: Single workflow reduces laboratory training burden, improves standardization and reduces error risk
Quality Performance
- Performance established using human RNA: Demonstrated Limits of Detection (LOD) of MR4.7 (0.002%IS) and LR 4.61, for the Major and minor kits, respectively, reflect “real-world testing” rather than cell line-based claims
- Multi-point Armored RNA®-based, IS-calibrated standards: Provide reproducible, traceable RNA quantification values
- All-inclusive reagents Quality Controlled: Complete offering reduces laboratory QC burden
*For Research Use Only. Not for use in diagnostic procedures.
†IS reporting only with QuantideX® qPCR BCR-ABL IS Kit.
QuantideX® BCR-ABL
Sensitive | Reliable | Simple
The QuantideX® BCR-ABL portfolio offers easy-to-implement testing solutions for the sensitive and reliable quantitation of Major (e13a2, e14a2) and minor (e1a2) BCR-ABL1 fusion transcripts for patients with chronic myeloid leukemia (CML).
The QuantideX® qPCR BCR-ABL IS Kit pairs best-in-class clinical sensitivity (MR4.7) with optimized laboratory efficiency, enabling deep molecular monitoring via a simple and standardized workflow. Featuring limited hands-on-time and automated data analysis, it enables any molecular lab to deliver accurate and clinically-meaningful results that physicians can trust. The QuantideX® qPCR BCR-ABL minor Kit builds upon these features and provides a robust and reliable testing solution for detection and ultra-sensitive monitoring of this rare but distinct leukemic variant.
Reduced Complexity
- Direct reporting on the IS†: Multi-point standard curve reduces variability and removes need for costly, complex sample exchange programs
- End-to-end workflow: Automated results reporting using QuantideX® Reporter software
Optimized Workflow
- Reduced hands-on time: Multiplexed design amplifies and detects both fusion and control gene in the same reaction
- Simplified inventory & quality management: All necessary RT and qPCR reagents and controls supplied in a single kit
- Common assay workflows across Major & minor: Single workflow reduces laboratory training burden, improves standardization and reduces error risk
Quality Performance
- Performance established using human RNA: Demonstrated Limits of Detection (LOD) of MR4.7 (0.002%IS) and LR 4.61, for the Major and minor kits, respectively, reflect “real-world testing” rather than cell line-based claims
- Multi-point Armored RNA®-based, IS-calibrated standards: Provide reproducible, traceable RNA quantification values
- All-inclusive reagents Quality Controlled: Complete offering reduces laboratory QC burden
†IS reporting only with QuantideX® qPCR BCR-ABL IS Kit.